Results from Miguel Seabra's research highlighted on international media


“How a gene breakthrough has saved Joe's sight - and, one day, the same technology could transform all our lives” is the piece published in the Daily Mail about Miguel Seabra research.

The piece covered the story of Joe Pepper who was diagnosed with choroideremia, a degenerative disease characterized by progressive vision loss. Choroideremia is caused by a mutation in a gene which usually produces a specific protein named REP-1 in the retina. Without this protein, the cells in the retina slowly die off. The pioneering research in this field has realized by Miguel Seabra at Imperial College London. It was found that a virus could be used to insert the correct DNA into cells so that missing protein is produced.

Please, find the complete article here.


Miguel Seabra is the principal investigator of Molecular Mechanisms Lab.